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Treatment for post stroke visual impairment – clinical practice versus literature evidence
The aim of this paper is to compare the treatments reported in a large scale stroke study (Vision in stroke (VIS) Study) against the treatments identified in a full systematic literature review. The purpose was to identify which treatment /...
Managing orbital compartment syndrome
This experimental study using cadaveric models was done to evaluate the surgical technique effective in relieving orbital compartment syndrome. Twelve cadaveric orbits were injected with blood analogue stained with fluorescein. Pressure probes were inserted in superotemporal (advanced 40mm into orbit)...
Cataract surgery in uveitis
This is a multicentre study of eight UK independent sites of patients with uveitis, undergoing cataract surgery between January 2010 and December 2014. A total of 1173 eyes were compared with a control reference group of 95,573 eyes from the...
Medical malpractice in uveitis: a review of clinical entities and outcomes
This paper presents a retrospective review of malpractice verdicts, rulings and settlements in the United States. Twenty-five cases of uveitis-related litigation spanning 1971-2014 were identified from the database representing 2.3% of all cases. Forty-eight percent of the cases were infectious....
Correlation between structural and functional status of optic nerve and retina in multiple sclerosis
Multiple sclerosis (MS) involves autoimmune inflammatory demyelination and axonal degeneration in the central nervous system. Investigation of the retina and optic nerve head (ONH) is an ideal way to visualise this demyelination. This study investigates the functional and structural properties...
CFEOM outcomes
This study presents the orbital and cranial magnetic resonance imaging (MRI) findings of patients diagnosed with congenital fibrosis of the extraocular muscles (CFEOM) along with the surgical procedures and outcomes for ocular motility and strabismus. Nine patients are described: three...
Complement factor B polymorphism and the phenotype of early age-related macular degeneration
The relationship between complement factor H (CFH) and age-related macular degeneration (AMD) is very well known, but other genetic polymorphisms relating to AMD are more poorly understood. This study was designed to investigate the relationship between complement factor B (CFB)...
The prevalence of macular cysts in patients with clinical cone-rod dystrophy determined by spectral domain optical coherence tomography
Cone-rod dystrophy is a progressive photoreceptor disorder which has multiple inheritance patterns. It is rare, with a prevalence of 1 in 40,000. Macular cysts are well recognised in other photoreceptor conditions such as retinitis pigments and choroideraemia, while they are...
Association between neuro-ophthalmology signs and chronic ataxia in children
Neuro-ophthalmological signs (N-OS) occur commonly in children with chronic ataxia. This study describes the N-OS and their frequencies, in general and by specific disease aetiology in paediatric patients with chronic ataxia. In total, 184 patients under the age of 17...
Systemic rituximab immunotherapy in the management of primary ocular adnexal lymphoma single institutional experience
Ocular adnexal lymphomas constitute 2% of all non-Hodgkin’s disease and 5-15% of all extranodal lymphomas and are usually localised, low-grade and of B-cell origin. This opens them up to potential treatment with a systemic monoclonal antibody-based drug (rituximab) directed at...
Corneal neurotisation with an allograft
This is the first reported use of an acellular nerve allograft for corneal neurotisation. Seven patients received a 7cm long commercially prepared acellular nerve allograft. This was coapted to a functioning supratrochlear, supraorbital or infraorbital nerve and then tunnelled to...
