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Swept-source OCT for measuring peripheral anterior synechiae

The authors report on a cross-sectional study looking at swept-source optical coherence tomography (SS-OCT) for measuring the area and degree of peripheral anterior synechiae (PAS) in patients with angle closure glaucoma. The SS-OCT is commercially available, has a laser wavelength...

Injection of methotrexate into silicone oil-filled eyes for grade C PVR

Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...

Corneal crosslinking in pellucid marginal degeneration

Fourteen studies were included in this first review examining the use of corneal-crosslinking (CXL) to treat pellucid marginal degeneration (PMD). PMD is a bilateral, non-inflammatory corneal thinning disorder characterised by inferior peripheral corneal thinning 1-3mm from the limbus in the...

Visual acuity outcomes in Coat’s disease by classification stage

This is a retrospective study of 160 consecutive patients with Coat’s disease under the Shields classification, with Snellen visual acuity (VA) pre and post treatment. Affected eyes were categorised based on the Shields classification: Stage 1: retinal telangiectasia onlyStage 2a:...

Quality of life after oculoplastic surgery

This is a literature review of published quality of life surveys in patients who have undergone a variety of oculoplastic procedures. The authors emphasise the importance of patient reported outcomes, noting that clinician and patient perceptions may differ, and that...

Correlation between aqueous flare and macular microvascular status in diabetes mellitus

The authors report a cross-sectional study which was conducted to investigate the correlation between aqueous flare and macular microvascular status, assessed by optic coherence tomography angiography (OCTA) in diabetes mellitus. Fifty-two diabetic patients with non-proliferative retinopathy, 44 diabetic patients without...

Contrast sensitivity in myopic eyes

A classification system has been proposed for myopic maculopathy: grade 0 (no myopic retinal lesions), grade 1 (tessellated fundus), grade 2 (diffuse chorioretinal atrophy (CRA)), grade 3 (patchy CRA), and grade 4 (macular atrophy). Tessellated fundus is defined as the...

Oral Ibuprofen reduces early bleb failure in high risk trabeculectomy

In this retrospective cohort study, 288 eyes of 273 patients (mean ±SD age: 68.56 ±10.47 y; 32.60% females) with primary glaucoma who underwent trabeculectomy / phacotrabeculectomy at the Singapore National Eye Centre between April 2020 and April 2021 with a...

My Top Five: Tips for a successful grant application in ophthalmology

Securing funding for an educational or research initiative in ophthalmology can often feel like a competitive, confusing and time-intensive task. Whether you’re an early-career researcher looking to get your first project off the ground or an experienced educator aiming to...

Birdshot retinochoroiditis

Birdshot retinochoroiditis (BRC) is a chronic, sight-threatening uveitis, most commonly affecting caucasian individuals in their fourth to sixth decades [1]. The disease is associated with HLA-29 and is characterised by progressive inflammation at the level of retina and choroid, with...

Protecting and recovering from email hacking

Over the last 12 months I have received emails from more than 20 friends and acquaintances (mostly doctors) who didn’t send those emails. More often than not I find the emails in my ‘Spam’ folder as Gmail knows they are...

Quantum imaging research could improve retinal scans

New EU-funded feasibility project is testing a quantum approach that could reveal finer detail in the eye than ever before. A European research consortium is exploring a new quantum imaging technique that could one day help clinicians see the earliest...