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Infliximab in treatment of PVR

In this phase 2 randomly controlled trial, 66 patients with primary rhegmatogenous retinal detachment and grade C proliferative vitreoretinopathy (PVR) were randomised in a 1:1 ratio to undergo pars plana vitrectomy (PPV) and silicone oil (SO) injection with or without...

Causes of abnormal head postures – literature review

Yadegari reports a narrative literature review for abnormal head postures (AHPs) with discussion on different causes. This review summarises the control of a normal head posture before discussing differences of ocular vs non-ocular AHPs. Ocular AHPs may be adopted to...

Cataract surgery in the extremely small eye: morphology, comorbidities and outcomes in 300 eyes

This is a retrospective study from Heidelberg University, Germany, between January 2009 to October 2023, including 300 eyes of 191 patients undergoing cataract surgery with short axial length requiring lens implantation of > 30 dioptres. Eyes were classified into the...

Usher syndrome patient reported outcomes

The authors present a systematic review of the literature on patient-reported outcomes in Usher syndrome; a leading cause of deaf-blindness. A total of 27 studies were included, and there was a strong bias towards studies from the US and Europe...

Idebenone for Leber hereditary optic neuropathy

The authors present a meta-analysis of studies reporting the effects of idebenone treatment on visual acuity (VA) in patients with Leber hereditary optic neuropathy (LHON), the most common inherited mitochondrial disorder. They included randomised controlled trials, non-randomised controlled trials and...

Genetic cause for idiopathic foveal hypoplasia

The authors present a small cohort study of 19 patients with idiopathic foveal hypoplasia diagnosed based on optical coherence tomography (OCT) features. Peripheral blood samples from all 19 patients underwent next-generation sequencing and 33 genes known to be involved in...