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Characteristics and incidence of sixth nerve palsy in children with intracranial hypertension

The authors report the incidence and characteristics of sixth cranial nerve palsy in paediatric patients with intracranial hypertension. A retrospective review of records was performed in central Ohio over a three year period and nine children were found to have...

Care providers view on how to improve care for paediatric conjunctivitis

The authors present a qualitative study. Purposeful sampling was used to recruit physicians or advanced practitioners for paediatric care in emergency, urgent or primary care settings. Semi-structured interviews were either held in-person or by telephone. All participants recruited commonly encountered...

Neuro-ophthalmology consequences of Lyme disease

This study sought to review the seasonality and the occurrence of Lyme disease within their institution with a focus on neuro-ophthalmic consequences. This was a retrospective study of 212 children: 50 (24%) with neuroborreliosis (NB). There was an increase in...

Silicone band loop myopexy as surgical treatment of myopic strabismus fixus in children

This study reports the outcomes of silicone band loop myopexy in a case series of seven children (10 eyes) with myopic strabismus fixus. There were five males and two females with a median age of five years (range 3–11). Six...

Leber’s hereditary optic neuropathy outcomes in an Indian population

A large cohort study in an Indian population is presented, with clinical and genetic profile analysis of patients with Leber’s hereditary optic neuropathy (LHON) treated over a five-year period. The study included 157 patients; 143 male, 14 female (10.2:1 ratio)...

Incomplete teprotumumab treatment for thyroid eye disease

This is a multi-centre retrospective analysis of clinical outcomes in patients who were on teprotumumab for thyroid eye disease but had the usual regime of eight infusions, three weeks apart, interrupted due to COVID-19. Manufacturing was suspended between Dec 2020...

Septo-optic dysplasia – a case note review

Septo-optic dysplasia (SOD) is a congenital disorder belonging to the midline brain malformation group. The condition manifests as a classical triad, including optic nerve hypoplasia (ONH), agenesis of midline structures (absent septum pel-lucidum and agenesis of the corpus callosum), and...

Genetic analysis of choroideremia families

Choroideremia (CHM) is a rare X linked recessive chorioretinal dystrophy. Symptoms include nyctalopia and progressive peripheral field loss. Female carriers may have mild symptoms. Choroideremia is known to be caused by a mutation in the CHM gene. A multicentre human...

Primary intravenous chemotherapy (IVC) for Group D retinoblastoma

A retrospective review is reported of 64 group D retinoblastoma (RB) eyes (52 patients) treated with primary IVC, between 2002 and 2014 from two centres, in the UK and US. The median age at presentation was 11 months, 35 (67%)...