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5387 results found

Emergency eye care in the UK: the way forward?

In this paper the authors highlight issues pertaining to the growing number of patients presenting to the emergency eye services in the UK. Data collection involved literature review, telephone surveys and email correspondence (n=142). Ninety-one lead clinicians responded and a...

Adjuvant oral voriconazole or oral ketoconazole for fungal keratitis

This randomised double-blinded trial examined clinical outcomes of 50 patients with severe fungal keratitis treated with either adjuvant oral voriconazole or oral ketoconazole. Inclusion criteria were culture or smear proven fungal ulcers >5mm in maximum diameter, involving >4mm of the...

Air or SF6 in DMEK

This retrospective study compared descemet’s membrane endothelial keratoplasty (DMEK) outcomes in 136 consecutive eyes of 68 patients. All patients underwent DMEK for Fuch’s endothelial dystrophy, where consecutive eyes received 100% air bubble during first eye surgery and 20% sulphur hexafluoride...

Platelet-rich fibrin for conjunctivoplasty after pterygium excision

The authors report a prospective, comparative, non-randomized clinical trial of 35 pterygium patients with unilateral nasal primary pterygium infiltrating the cornea 2-5mm in size, who underwent pterygium excision between June 2013 and September 2014. Thirty-five eyes of 35 patients with...

Ologen Collagen Matrix to treat ocular hypotony after filtration glaucoma surgery

The authors report a retrospective, observational case series of a Japanese cohort. 12 consecutive implantations of ologen in nine eyes of nine subjects (five men, four women; mean age ±SD, 72.1±12.7 years) who underwent subconjunctival implantation of the device to...

Systemic screening in adnexal lymphoma

This is a retrospective review of 119 patients diagnosed with ocular adnexal lymphoma, 85 of whom had primary adnexal disease and 34 had previously been diagnosed with lymphoma outside the ocular adnexa. Sixty-eight of the primary and 24 of the...

OCT measures of lateral and medial recti

The authors assessed the agreement of the measurements of the horizontal rectus muscle insertion distance to the limbus and the muscle thickness between three different OCT devices. This was a cross section observation study of 70 eyes of 35 subjects....

IAC vs. IVC chemotherapy for RB

This a single centre retrospective review of consecutive patients between 1997 and 2014, of all sporadic unilateral retinoblastoma (RB) group D cases, treated with combined intravenous chemotherapy (IVC) and focal treatments (1997- 2008), or intra-arterial chemotherapy (IAC) treatment (2008 to...

Systemic pharmacology of intravitreal anti-VEGF

This study aimed to evaluate and compare serum drug concentrations and plasma free-VEGF concentrations in patients with AMD, DME, or RVO receiving intravitreal injections of aflibercept, bevacizumab or ranibizumab. This prospective study enrolled patients from several offices of a single...

Clinical characteristics and outcomes of open globe injury

This retrospective cohort study examined consecutive open globe injuries at a tertiary referral centre over a three year period. The aim of the study was to detail the clinical characteristics of open globe injuries and to explore their association with...

Phaco-ECP vs. Phaco alone to treat glaucoma

This retrospective review compared combined phacoemulsification and endoscopic cyclophotocoagulation (phaco-ECP) to phaco alone in patients with mild to moderate glaucoma. Outcome measures included cumulative full and qualified success survival, postintervention IOP and ocular anti-hypertensive medication reduction. Full success was defined...

A phase 3 randomised trial of nicotinamide for skin cancer chemoprevention

To B3, or not to B3? That was the question asked in this controlled trial in which the authors were able to show that oral nicotinamide (vitamin B3) is able to reduce further skin cancer development in high risk patients....