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Ophthalmic presentations and outcomes in Erdheim-Chester disease

This is a comprehensive article describing clinical manifestations and pathogenesis of Erdheim-Chester disease (ECD) followed by a literature review of the available treatments. The authors look to compare historical treatment (HT) with vemurafenib, a BRAF inhibitor. ECD is a non-Langerhans...

Differentiating orbital cellulitis from non-specific orbital inflammation

This is a retrospective study looking at whether common laboratory investigations can help differentiate between orbital cellulitis (OC) and non-specific orbital inflammation (NSOI). NSOI is a diagnosis of exclusion following negative investigations for systemic diseases such as IgG4-related disease, granulomatosis...

Testing of binocular contrast sensitivity as an objective measure of severity in intermittent exotropia

The purpose of this study was to compare the binocular contrast sensitivity ratio (measured with the Vision CSV-100 vector chart) between 40 intermittent exotropia patients and 40 normal controls. The authors also evaluated the effect of intermittent exotropia compensation status...

Inferior oblique muscle features

The authors aimed to study and morphometrically define the surgical anatomy of the inferior oblique muscle and its variations, and to outline surgical coordinates to aid location of the inferior oblique origin and nerve supply to the inferior oblique muscle....

Acute comitant esotropia as the presenting sign of diffuse intrinsic pontine glioma

The authors present four children with acute comitant esotropia (AACE) associated with diffuse intrinsic pontine glioma. All were treated with radiation therapy and all subsequently died due to the tumour. Children were aged 5, 5, 4.5 and 11 years. General...

Smartphone use impact on accommodation and convergence measures

This study aimed to explore the relationship between smartphone use impact on the mean triad and potential pre-existent risk factors for acute acquired comitant esotropia (AACE). A prospective study of 18 university staff and students aged 24 years (SD 7.7)...

Aquaporin-4 antibody testing in isolate optic neuritis

The authors present a retrospective case review of first presentation isolated cases of optic neuritis tested for aquaporin-4 antibody across two centres over a nine-year period. Exclusion criteria included known diagnosis or other manifestations of neuromyelitis optica spectrum disorder. Two...

Telemedicine for postoperative reviews

This is a detailed study looking at the use of telemedicine in the context of a postoperative review following oculoplastic and orbital surgery. The authors combined a video consultation (telephone if there were technical issues) with a ‘pre-visit tool’ that...

Prevalence and related factors for strabismus and amblyopia in Africa

The aim of this study was to overview the literature in relation to strabismus and amblyopia and associated risk factors in Africa. The review included 24 papers; eight for strabismus and 21 for amblyopia. Sample sizes ranged from 352 to...

Visual snow syndrome: a review

Visual snow syndrome (VSS) is a neurological condition characterised by visual phenomena described as dots moving across the visual field. Other visual symptoms can take the form of palinopsia, entopic phenomena, photophobia and nyctalopia. Tinnitus and migraine can be commonly...

Surgical correction of lacrimal gland prolapse

This is a systematic review of published literature on the management of lacrimal gland prolapse or ptosis. The authors found 16 publications which contained a description of any surgical correction of a prolapsed lacrimal gland, comprising seven case reports, four...

Eye disorders occurring in congenital CMV

The aim of this study was to examine the relationship between congenital cytomegalovirus (CMV) infection and ophthalmological disorders that occur in children and record the frequency and type of eye disorders that occur from the infection. Of 449 potential studies,...