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Benefit of selenium and vitamin D supplementation in thyroid eye disease

There is some limited evidence of as association between thyroid eye disease (TED) and nutritional deficiencies including selenium and vitamin D. Prior studies show that selenium can reduce TPO-antibody concentrations and improve hypothyroidism and post-partum thyroiditis. Limited evidence also shows...

Validity of coding in neuro-ophthalmology within large administrative datasets

A systematic review of validation studies of the International Classification of Disease (ICD) coding system, ICD-9 and ICD-10 is presented by the authors. Three searches were conducted based on three concepts, firstly health administration claims and ICD codes, secondly diagnostic...

IOL effect on refraction

The authors aimed to evaluate the effect of age at primary intraocular lens (IOL) implantation on the rate of refractive growth during childhood. This was a retrospective study of 296 eyes of 219 patients. Forty-six met inclusion criteria; 28 unilateral...

Accuracy of clinician vs. radiologic interpretation of the imaging of orbital lesions

This is a retrospective study of 242 patients who underwent surgical orbitomy at University of California Davis Health between 1 January 2000 and 20 May 2019. The preoperative imaging with radiologist’s interpretation, clinical assessment with clinician’s interpretation of imaging, and...

How common is optic disc drusen in young patients with NAION?

A retrospective notes review at two tertiary care centres was completed between 2009 and 2019. The inclusion criteria for the study was a diagnosis of nonarteritic anterior ischaemic optic neuropathy (NAION) in at least one eye, aged between 18 and...

Using lumbar puncture as a diagnostic tool of IIH when the presentation is typical

The authors present the findings of a retrospective observational chart review across three neuro-ophthalmology clinics. Databases at each clinic were searched using inclusion criteria based on established diagnostic criteria for idiopathic intracranial hypertension (IIH). Cases with missing data, atypical findings...

ROPScore for detection of any and severe ROP

ROPScore is a free tool consisting of a logistic regression equation to calculate the risk per child and calculated one time per infant at six weeks of life. It helps to predict severe retinopathy of prematurity (ROP). This study aimed...

RCT of VR training versus occlusion for amblyopia

The purpose of this study was to compare the visual outcomes of occlusion with game playing through a virtual reality (VR) system in children with unilateral amblyopia. The study was undertaken at the Negah Eye Hospital in Iran. This was...

Review of paediatric open globe injuries in the US

This study used the Nationwide Inpatient Sample (NIS) database to describe the trends in types, demographics and incidence of paediatric open globe injuries in the US. The NIS database covers about 97% of the US population and about 20% of...

New prognostic model for multiple sclerosis after optic neuritis presentation

The authors present a post-hoc analysis using the publicly available data set from the Optic Neuritis Treatment Trial. The Cox proportional hazards regression models were used to assess for associations between clinical and radiological variables and the development of clinical...

Causes of childhood open globe injuries sustained during playtime

This study explored the possible mechanisms of paediatric open globe injuries that occurred during playtime and required surgical treatment. The study was conducted in a single centre in Egypt. This was a prospective study of all children admitted with open...

Amblyopia treatment outcomes across different US insurance groups

The authors report a lack of research comparing outcomes, appointment attendance and treatment compliance between those on Medicaid vs those with private insurance in the USA for amblyopia treatment. The aim of this study was to compare outcomes of amblyopia...