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681 results found

The long-term effects of AREDS on AMD progression

The Age-Related Eye Disease Study (AREDS) was an 11-centre, double-masked, clinical trial that in 2001 found a high-dose of antioxidant vitamins plus zinc was effective in protecting against progression of age-related macular degeneration (AMD) in patients with moderate to high...

Comparison of changes in ECD and CCT between CPS and FLACS

This is an intraindividual randomised clinical trial of 134 eyes from 67 patients, one eye was treated with femtosecond laser-assisted cataract surgery (FLACS) (including pretreatment of main incision, side port, capsulotomy and lens fragmentation) and the fellow eye received conventional...

Choice of cycloplegia regime

The purpose of this randomised control trial (RCT) was primarily to compare the refractive outcome of atropine 0.5% (A) instilled twice daily at home 2.5 days before measurement versus two drops of 1% cyclopentolate (CC) in one eye versus one...

Visual retraining for homonymous hemianopia following stroke

This is a clinical trial evaluating the efficacy of motion discrimination training as a potential therapy for stroke-induced hemianopic visual field defects involving 48 patients. They were randomised into two arms, one intervention (deficit-field) and one control (sighted-field). Patients were...

Effect of observation of intermittent exotropia on health-related quality of life of children and parents

The authors present the analysis of the Intermittent Exotropia Questionnaire (IXTQ) completed by the observation arm of a previously reported randomised controlled trial comparing part-time patching to observation. Children aged >5 years completed the Child IXTQ, and all parents completed...

RCT of VR training versus occlusion for amblyopia

The purpose of this study was to compare the visual outcomes of occlusion with game playing through a virtual reality (VR) system in children with unilateral amblyopia. The study was undertaken at the Negah Eye Hospital in Iran. This was...

Pilot trial of virtual reality to treat amblyopia beyond the age of seven years

A pilot double-blind randomised controlled trial is presented. Patients were required to be between seven and 38 years of age, have a diagnosis of anisometropic and / or strabismus unilateral amblyopia, visual acuity in the amblyopic eye between 0.3-1.0 LogMAR...

Patients prefer vision from lasik than from smile in a contralateral-eye trial

This prospective, randomised, single surgeon, contralateral-eye clinical trial compared the results in myopic patients undergoing wavefront-guided femtosecond laser in situ keratomileusis (LASIK) in one eye and small-incision lenticule extraction (SMILE) in the fellow eye. The patient-reported outcomes with laser in...

RCT of unilateral vs bilateral surgery for lateral incomitance in exotropia

The purpose of this study was to evaluate and compare the surgical outcomes in the management of lateral incomitance with regard to ocular alignment and change in lateral incomitance in cases of bilateral vs. unilateral strabismus surgery. This was a...

Randomised controlled trial for large-angle exotropia surgery

The purpose of this study was to investigate single eye, single setting surgical options to correct 80–90PD of exotropia with two options of muscle transplant and suture hang-back recession. There was retention of anatomical limits of 6mm resection for medial...

Infliximab in treatment of PVR

In this phase 2 randomly controlled trial, 66 patients with primary rhegmatogenous retinal detachment and grade C proliferative vitreoretinopathy (PVR) were randomised in a 1:1 ratio to undergo pars plana vitrectomy (PPV) and silicone oil (SO) injection with or without...

Addressing diabetes-related complications in Tanzania and Eswatini: A comprehensive approach to eye and foot screening

Diabetes is rising globally, particularly in low- to middle-income countries (LMICs), where healthcare systems are under resourced [1,2]. Among its complications, diabetic retinopathy (DR) and diabetic foot disease are preventable yet frequently overlooked [3-6]. These problems often develop together due...