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Froben for anterior scleritis
Flurbiprofen (Froben) is one of the nonselective cyclooxygenase (COX) inhibitors blocking both COX-1 and COX-2 pathways. Agrawal et al. undertook a retrospective cohort study to determine the effectiveness of oral Froben in managing noninfectious, non-necrotising anterior scleritis. One hundred and...
Anterior segment OCT imaging in cases of episcleritis and scleritis
The purpose of this study was to determine whether it is feasible to obtain good-quality images with anterior segment OCT (AS-OCT) in patients with episcleral or scleral inflammation located anterior to the equator, and whether this technique is able to...
Intravitreal triamcinolone for uveitic macular oedema
This paper from South Korea reports on a prospective, double blind, randomised clinical study designed to evaluate the additional benefit of intravitreal triamcinolone (TA) administration for noninfectious uveitic macular oedema as an adjunct therapy to systemic anti-inflammatory treatment. Patients were...
Ozurdex use in noninfectious uveitis
Burkholder et al. reported the practice patterns of 45 respondents of approximately 176 surveyed members of the American Uveitis Society regarding the use of the Ozurdex implant. Most respondents performed the injection in either a procedure (41.0%) or clinic (23.1%)...
Recurrent thyroid eye disease
This study investigates the incidence of recurrent thyroid eye disease. The authors retrospectively reviewed the records of 415 patients who had been diagnosed with thyroid eye disease between 2006 and 2012. The medical notes were scrutinised for evidence of a...
Bupivicaine injection for Bell’s palsy
This study assesses the use of intramuscular bupivicaine to treat lid retraction and lagophthalmos in facial palsy. It is a prospective non-comparative interventional series of 10 patients with Bell’s palsy (House-Brackman grade IV or V) who each received three serial...
RTP801 as a neuroprotective and axon regenerative treatment
This paper describes the neuroprotective and axon regenerative effects of siRTP801, which is a translatable small-interfering RNA (siRNA) targeting mTOR negative regulator; RTP801, through in-vivo and in-vitro models. In-vivo studies involved an optic nerve crush rat model with intravitreal injections...
Association between serum levels of testosterone and estradiol with meibomian gland assessments in postmenopausal women
This study aims to reveal any correlation between serum levels of testosterone and estradiol in postmenopausal women with meibomian gland dysfunction. Postmenopausal subjects were defined as amenorrhoea for at least one year with low follide stimulating hormone (FSH) and estradiol....
Comparison of SS-OCT and SD-OCT in polypoidal choroidal vasculopathy
Swept source OCT (SS-OCT) is known to have a longer wavelength than spectral domain OCT (SD-OCT), allowing deeper penetration into retinal and choroidal layers. The aim of this study was to investigate whether SS-OCT is superior to SD-OCT in imaging...
Bleb-related changes in upper lid position
This is a review of five patients with upper lid ptosis or lid retraction secondary to large filtering blebs post-trabeculectomy. The authors review each case and apply a model to analyse the separate forces acting on the upper lid to...
Allergic eyelid dermatitis
This is a retrospective 12 year review of 61 patients diagnosed with periocular allergic dermatitis. The average age was 66 years, with 74% being female. The commonest indications for referral were epiphora, ectropion and blepharitis; and the main symptoms were...
