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Retrograde maculopathy in glaucoma

Macular optical coherence tomography (OCT) analysis can be used for quantitative measures of optic nerve atrophy at a location far away from the optic nerve head. This has recently led to the discovery of microcystic macular oedema (MME), in the...

Scheimpflug images and graft rejection

This study aimed to assess corneal changes using 360-degree Scheimpflug images and pachymetry readings to outline screening parameters, which define graft rejection. Seventeen eyes of 16 patients developed clinically manifest allograft rejection two to 42 months after surgery – those...

Effects of orbital decompression

This is a retrospective review of 319 orbital decompression operations in 169 patients (73% female) with thyroid eye disease. Three wall decompressions were performed in 92 eyes, 2-wall in 206 (medial and floor), and a single wall (medial) in 18,...

Twenty-four hour IOP patterns in patients with thyroid eye disease (OO/GL)

Elevated IOP in patients with thyroid eye disease (TED) can be caused by restriction and compression of the globe by enlarged extraocular muscles, elevated episcleral venous pressure and increased mucopolysaccharide deposition in the trabecular meshwork. Although previous studies have investigated...

Effect of anti-VEGF treatment on PED morphology

This retrospective study of 30 eyes assessed the effect of anti-VEGF on morphology of pigment epithelial detachments (PED) secondary to age-related macular degeneration (AMD). Thirty eyes of 28 patients with PED were compared to 30 eyes of 30 patients with...

Are retinal vein occlusions seasonal? And if so why might that be?

Some studies have reported a strong seasonal pattern to central retinal vein occlusion (CRVO) occurrence with a peak in January, but other studies have failed to replicate this finding. The authors sought to determine data for Stockholm’s seasonal variation in...

The choroid in pregnancy

During pregnancy there can be different types of ocular changes including a decrease in corneal sensitivity, increase in central corneal thickness and curvature, decrease in intraocular pressure, central serous chorioretinopathy and ocular blood flow. Advances in ophthalmic imaging devices has...

New mouse model of diabetes mellitus

Diabetic retinopathy (DR) is a serious complication of diabetes. It is driven by the loss of pericytes, cells which control vascular function, due to excess formation of sugar alcohols by the enzyme aldose reductase (AR). AR has been shown to...

Prostaglandin levels in femto cataract surgery

Following previous reports of pupil size decrease after femtosecond treatment, the authors compare levels of prostaglandins in patients undergoing femtosecond assisted cataract surgery with those having routine cataract surgery. Patients with inflammatory eye disease, previous trauma surgery, age-related macular degeneration...

Effect of change in retinal nerve fibre layer thickness on quality of life in patients with glaucoma

The authors investigated the relationship between structural changes in glaucoma (retinal nerve fibre layer (RNFL) thickness) and quality of life (as measured by the NEI VFQ-25 questionnaire) over a period of time. Two hundred and sixty eyes of 130 patients...

Metamorphopsia in idiopathic epiretinal membranes

The Amsler grid is commonly used for self-monitoring, but is qualitative and has low sensitivity. The M-chart reduces the amount of spatial redundancy (‘filling in’) in the Amsler grid. The Orientation Discrimination (OD) test studied in this paper consists of...

Microvascular disease in Alport syndrome

The authors present the findings of a retrospective case-control observational study on increased microvascular disease in individuals with Alport syndrome recruited over a 21-year period. They recruited 28 males and 28 females with X-linked Alport syndrome (XLAS) and eight men...