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MicroRNA mediate retinoblastoma signal transduction

MicroRNAs (miR) are small non-coding single-stranded RNA molecules, normally 22 nucleotides long. There is a large family of miR that control protein expression by binding to mRNAs, leading to their degradation. One important role of miR is in tumours where...

Certifying patients as visually impaired: the start of a journey

In March 2017 there were 290,475 people registered as either visually impaired or severely visually impaired in the UK [1]. Patients registered as sight impaired benefit from financial support as well as practical help. Practical help is provided by social...

Ambient scribes: The silent revolution

Clinical practice is in the midst of a profound digital transformation with a new wave of technology gaining increasing prominence: ambient scribes. These AI-powered tools streamline documentation by converting doctor–patient conversations into structured clinical notes in near real time. Healthcare...

Quality of esotropia referrals

The purpose was to examine the quality of referrals made for children with esotropia and to evaluate management offered prior to referral. This retrospective study identified 326 children with esotropia aged less than five years and referred over a period...

21st Century retinal laser treatment in the anti-VEGF era

In today’s world, macular laser treatment has a vital role in the treatment of diabetic macular oedema (DMO). DMO is one of the most common causes of visual impairment. Despite expensive intravitreal treatment courses of anti-VEGF, many will agree that...

Nominations open for AOP elected and designated Council positions

The Association of Optometrists invites nominations from eligible members for its 2024 Council elections.

Preparing for the Duke Elder Award

The Duke Elder examination is an undergraduate ophthalmology exam, conducted by the Royal College of Ophthalmologists (RCOphth) and undertaken by students with an interest in ophthalmology. It is a two-hour, 90-question, multiple choice exam with a broader curriculum than that...

Enhancing ophthalmology training: Unleashing the power of simulation

Ethical and practical barriers hinder early surgical experience in ophthalmology training [1], which is problematic when early-career trainees bring a higher risk of poor surgical outcomes and patient harm [2]. The European working time directive and the surgical backlog secondary...

Assessment of slow and fast vergence in stroke survivors

The authors present the findings of a prospective cohort study. Three hundred and five stroke survivors were recruited consecutively. The following exclusion criteria were applied; aphasia, cognitive impairment, visual inattention, ocular motor nerve palsy and neuromuscular disease. Fifty age-matched controls...

Blame the lens – not its position – in refractive surprise

Aetiology of postoperative refractive surprise Weber coined the term “wrong eye, wrong intraocular lens, wrong patient” in 2008 as an aide memoir of major factors believed to underlie refractive surprise – defined as a significant unintended difference between dioptric refraction...

DOs study myopia management at ABDO’s NRC

The Association of British Dispensing Opticians (ABDO) has held the first Myopia Management Conference in Birmingham this week.

Optical Express sponsors Atlantic rowing challenge for dementia research

Optical Express has become the official headline sponsor of a rowing challenge that will see Jason Black (52) and Neil Glover (60) row over 3100 miles across the Atlantic Ocean, in an effort to raise money to fund groundbreaking research into a cure for dementia.