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Postoperative endophthalmitis is arguably the worse possible complication of cataract surgery. We are a victim of our own success as the procedure has such an amazing safety profile that when things go wrong patients are bound to feel aggrieved and...The next wave of AI in ophthalmology: From screening to communication
Artificial intelligence (AI) is reshaping ophthalmology, moving from research laboratories into everyday clinical care [1]. With its strong reliance on imaging and pattern recognition, ophthalmology is uniquely positioned to benefit from AI innovations. These developments range from autonomous disease screening...
Corneal stroma modelling under hypoxic conditions
The cornea is exposed to hypoxia under several conditions including sleep, inflammation and wound healing. Being an avascular tissue to maintain transparency, how the cornea homeostatic controls oxygen tension is important. To address this process two models were utilised; a...
Enzymatic clearance of anterior chamber infiltrate in uveitis
Aqueous humour (AH) which fills the anterior chamber (AC) of the eye provides nutrients to the cornea and the lens. Clearance of cellular and particular matter from AH is necessary for good visual acuity. In part this is achieved by...A golden garden featuring famous voices among the medals at RHS Sandringham
Leading sight loss charity RNIB (Royal National Institute of Blind People) has landed three medals at a prestigious Norfolk flower show with a garden championing the power of storytelling. The imaginative design of the RNIB Talking Books Garden caught the...Doctor in the House
“What’s the bleeding time?”“10 past 10 sir”. These are the famous lines uttered by Chief Surgeon Sir Lancelot Spratt (James Robertson Justice) and Medical Student Simon Sparrow (Dirk Bogarde) on a pre-op ward round at the fictional St Swithin’s Hospital,...
Corneal lenticule allotransplant
This animal study looked at corneal lenticule allograft transplantation in rabbits. Seven rabbits underwent small incision lenticule extraction (SMILE) procedures, where their stromal lenticules were extracted and transplanted fresh into pre-prepared corneal stromal pockets of seven recipient eyes. Animals were...Identifying drugs associated with intraoperative floppy iris syndrome
Before David Chang MD from the University of California found out about intraoperative floppy iris syndrome (IFIS), ophthalmologists were mystified each time they came across cataract surgeries that were characterised by sudden intraoperative iris prolapse and pupil constriction. The biggest...Acute uveitis from late migration of soft lens matter 10 years post cataract surgery
A 58-year-old Caucasian male presented to the emergency eye clinic with a two-day history of a painful, red left eye and blurred vision. His past ocular history included uncomplicated left phacoemulsification cataract surgery in 2010 and left retinal detachment repair...
