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The compendium to clinical evidence in DMO treatment
This review article summarises the current evidence base in the treatment options for diabetic macular oedema (DMO). The authors have included many real-world data studies that provided valuable insights into the optimal management of DMO. The authors argue that these...
Progression of macular atrophy in Stargardt disease
The authors present a study of a cohort of patients with genetically proven ABCA4 gene mutation related Stargardt disease. They aimed to quantify the effect of lesion location and topography on disease progression using fundus autofluorescence imaging. One hundred and...
Randomised controlled trial for large-angle exotropia surgery
The purpose of this study was to investigate single eye, single setting surgical options to correct 80–90PD of exotropia with two options of muscle transplant and suture hang-back recession. There was retention of anatomical limits of 6mm resection for medial...
Is thrombolytic treatment warranted for central retinal artery occlusion?
Central retinal artery occlusion (CRAO) is a subtype of acute ischaemic stroke which results in severe visual loss. Acute CRAO is equivalent to a brain acute ischaemic stroke (AIS), as the obstruction of the central retinal artery (CRA) causes end-organ...
Review of efficacy and safety of tetracaine drops in strabismus surgery
Tetracaine is a topical anaesthetic drug used to anesthetise the eye and surrounding areas during strabismus surgery. It is generally safe and well tolerated but can cause mild adverse reactions at the site of use and, in rare cases, serious...
Orbital fat density as a diagnostic tool in pre-septal and orbital cellulitis
This study aimed to evaluate the usefulness of orbital fat density in identifying post-septal involvement when initial differential diagnosis between orbital (OC) and periorbital (POC) cellulitis is unclear. This was a retrospective study of 57 patients with clinical diagnosis of...
Types of nystagmus and associations in a large international database for nystagmus
The authors aimed to characterise a large international cohort of children with nystagmus. Data were taken from a prospective database which was started in 2010. Up to 2020, this contained 1774 patients with nystagmus from 38 US states and 30...
Updated staging of LCHADD retinopathy
The authors present their proposal for an updated staging system for Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase (LCHAD) deficiency retinopathy. This is a rare mitochondrial disease due to deficiency of the long chain fatty acid oxidation pathway. Forty patients who were part of...
Ahmed and Baerveldt glaucoma drainage implant outcomes
This study reports the surgical outcomes of both the Ahmed (AGV) and Baerveldt (BGI) glaucoma drainage implants in a cohort of patients with primary congenital glaucoma over a long follow-up in a single tertiary centre. This was a retrospective study...
BT vs primary surgery for infantile esotropia
In this study, the success rate of treatment for infantile esotropia (IET) patients who had surgery because of under correction after botulinum toxin (BT) is compared to those having primary surgery. The study included 52 patients (27 male) with mean...
Long-term treatment for diabetic macular oedema
The authors set out to characterise anti-VEGF treatment patterns and long-term outcomes in patients with diabetic macular oedema. A retrospective analysis of over 190 thousand patients on the Intelligent Research in Sight registry was performed. Of these, 1236 eyes have...
