You searched for "Blindness"
Outcomes of ‘treat and extend’ for neovascular AMD
1 August 2015
| Brian Ang
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EYE - Vitreo-Retinal
The authors report on 24-month outcomes of anti-vascular endothelial growth factor (anti-VEGF) therapy using a ‘treat and extend’ regime for treatment-naïve neovascular age-related macular degeneration (nAMD). Data for this study was collected from the Fight Retinal Blindness observational registry based...
Ovarian hormones drive onset of Sjogren’s disease in mice
1 December 2014
| Graham Wallace
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EYE - Cornea, EYE - General
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Sjögren’s Syndrome, lacrimal glands, sex hormones, cytokines, anti-Ro/SSA, anti-La/SSB, NOD.B10.H2b
Sjogren’s syndrome (SS) is a debilitating, sight-threatening, systemic autoimmune disease with no effective treatment available. SS is characterised by lacrimal gland lymphocytic infiltration and epithelial cell death, as well as by the presence of serum autoantibodies. Patients have severe dry...
Visual prognosis in Irish Leber’s hereditary optic neuropathy
1 December 2022
| Claire Howard
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EYE - Neuro-ophthalmology
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Leber’s hereditary optic neuropathy, idebenone, inherited optic neuropathy, mtDNA, ophthalmic genetics, optic atrophy
Leber’s hereditary optic neuropathy (LHON) is an inherited optic neuropathy This paper presents a retrospective review of clinical data from patients with LHON presenting to an Irish tertiary referral ophthalmic hospital. Clinical and genetic characteristics were assessed for useful biomarkers...
Effects of ML4 on the eye
Mucolipidosis type IV (ML4) is an autosomal recessive lysosomal storage disease and is caused by variants of the MC0LN1 gene. It often presents in young individuals with eye and ocular adnexa issues. The authors present a case report and literature...
Impact of WASH factors on trachoma prevalence
4 December 2024
| Nishita Patel
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EYE - Cornea
Trachoma is the leading infectious cause of blindness globally. Following a national population-based trachoma survey in Malawi, one round of azithromycin mass drug elimination (MDA) was carried out successfully – that is, the prevalence of trachomatous inflammation, follicular (TF) in...
In conversation with Yasmin El-Rouby
2 February 2024
| Yasmin El-Rouby
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EYE - General
Author and Eye Doctor, Dr Yasmin El-Rouby, wishes to raise awareness about common vision disorders. Envisioning a world where preventable eye conditions are caught early, she founded Baseera, a non-profit organisation, to improve access to basic eyecare in developing countries....
Orbis and FedEx team up on three-week training for Eye Care Professionals in Vietnam
This is the first surgical project for the Orbis Flying Eye Hospital in three years.Genetic therapy gives infants life-changing improvements in sight
24 February 2025
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genetics, gene therapy, Moorfields, paediatrics, research, new, AIPL1, Leber Congenital Amaurosis
Four young children have gained life-changing improvements in sight following treatment with a pioneering new genetic medicine through Moorfields Eye Hospital and UCL Institute of Ophthalmology, with the support of MeiraGTx. The children were born with a severe impairment to...
Making a life-changing difference in Bangladesh
1 October 2016
| Sheik Rahman
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EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
It has always been a desire of mine to volunteer in a ‘vision aid’ type project abroad, but due to various factors I had not been able to fulfil this desire until very recently. A gentleman called Mizanur Rahman (founder...
IN FOCUS - Beyond 2020: what next for global eye health?
1 April 2020
| Peter Holland
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EYE - General
The year 2020 is a pivotal year for global eye health. It marks the conclusion of ‘VISION 2020: The Right to Sight’ which has guided action for the past two decades, and the end of the World Health Organization (WHO)...
Understanding the inequalities of ophthalmic care for Indigenous people in a first world country
Aboriginal Australians have faced numerous challenges over the past centuries. Here in this article, Edward Saxton highlights why there are inequalities of ophthalmic care in Australia and why this has led to increased levels of blindness in Aboriginal people relative...Tackling diabetic retinopathy globally through the VISION 2020 LINKS Diabetic Retinopathy Network
1 February 2017
| Nick Astbury, Philip Burgess, Allen Foster (Prof), Denise Mabey, Marcia Zondervan
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EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
It is abundantly clear that the burden of diabetes is rapidly increasing, as there are now 415 million adults with diabetes in the world, with a projected rise to 642 million by 2040 [1]. This equates to 1 in 10...
