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1369 results found

Canadian centre experience with ocular cystinosis cases

Ocular cystinosis (OC) is an uncommon recessive genetic disease occurring in about one case per 100–200,000 live births. Patients have accumulation of cystine crystals within tissues. Ocular symptoms include photophobia, blepharospasm, foreign body sensation, retinopathy and visual impairment. Crystals have...

Clinical outcomes following intraluminal stent removal from the PAUL glaucoma implant

This single German centre retrospective cohort study included 70 eyes from 68 patients. Qualified and complete success rates (95% CI) were 92.9% and 55.7% after 1 year and 88.6% (81.4–95.7%) and 50% (37.1–62.9%) at the last follow-up time point for...

Ocular sequalae of spinal muscular atrophy

The authors present a retrospective single-centre cohort study of patients with spinal muscular atrophy – a neurodegenerative disorder presenting between infancy and early adulthood. Forty-eight patients were included in total, with roughly equal numbers of types 1, 2 and 3...

Ocular sequalae of spinal muscular atrophy

he authors present a retrospective single-centre cohort study of patients with spinal muscular atrophy – a neurodegenerative disorder presenting between infancy and early adulthood. Forty-eight patients were included in total, with roughly equal numbers of types 1, 2 and 3...

Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity

Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...

Prevalence of acute anterior uveitis in diabetic patients attending diabetic eye disease clinics

The authors share their investigation at Manchester Royal Eye Hospital into the association between diabetes and AAU. The global prevalence of diabetes mellitus (DM) is rapidly rising from an estimated 9.3% in 2019 to 10.2% by 2030 [1]. The link...

Strengthening the signal: Advancing oculomics research for systemic health insights

Oculomics, the study of how ocular structure reflects systemic health, is poised to become an integral tool for predicting, triaging, and diagnosing a wide range of diseases. By analysing data from the eye, particularly the retina, healthcare providers can gain...

Management of diabetic macular oedema in vitrectomised eyes

Diabetic macular oedema (DMO) is one of the leading causes of blindness; its prevalence is on the rise with progressive increase in numbers of people suffering from diabetes. The management of DMO has evolved significantly over the past few years....

How to get a trainee from 0 to 600 cataracts in two years: Perspectives from the trainee and the trainer

Trainee’s perspective I remember my first day as an ST1 at Moorfields Eye Hospital in Croydon. I was in theatre for a cataract list, and the challenges were numerous. From draping to hydrating the wound, it was all completely new...

Large language models in ophthalmology

Traditional artificial intelligence (AI) models typically require large amounts of labelled data for training. For example, to develop a model capable of detecting macular pathologies on optical coherence tomography scans, thousands of scans would need to be manually labelled by...

My Top Five: Tips for a successful grant application in ophthalmology

Securing funding for an educational or research initiative in ophthalmology can often feel like a competitive, confusing and time-intensive task. Whether you’re an early-career researcher looking to get your first project off the ground or an experienced educator aiming to...

Safety and efficacy of a nurse-led intravitreal injection service using an Precivia® injection assist device

Nurse-led intravitreal injections have become of great importance for busy eye units. In this article, the authors present safety data from five years of a nurse-led service with the use of the Precivia® intravitreal injection assist device. Intravitreal injections of...