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Researchers identify a novel genetic cause of Fuchs endothelial corneal dystrophy

2 October 2025 | cornea, genetics, research, novel therapies, age-related vision loss
Researchers identify a novel genetic cause of Fuchs endothelial corneal dystrophy, offering new ways for future therapies to target this common, age-related cause of visual loss. In a landmark study, researchers supported by NIHR Moorfields Biomedical Research Centre, have identified...

AI detects eye changes that lead to sight loss in young people

16 October 2025 | artificial intelligence, kerataconus, Moorfields, sight loss
Use of Artificial Intelligence (AI) can accurately predict when young people with the sight- threatening eye condition kerataconus need treatment to stabilise the cornea and prevent loss of vision. Developed by researchers at Moorfields Eye Hospital and UCL Institute of...

“I can see fine. Why do I need my eyes tested?”

2 December 2019 | | EYE - General
Are routine eye examinations really necessary? The author asks whether frequent appointments in low-risk patients with normal results are actually cost-effective. It’s recommended that most people should get their eyes tested every two years.” [1] This message is widely publicised...

Developing community eye care: the evolution of Wales’ eye care services

1 April 2020 | | EYE - General
In the third in our series about community eye care in the home nations, David O’Sullivan explains how Wales has developed its community eye care services. Since the devolution of healthcare to Wales on 1 July 1999 [1], significant changes...

Providing primary eyecare services during a global pandemic: the new normal

7 December 2020 | | EYE - General
It would be fair to say that 2020 hasn’t quite turned out to be the year that anyone predicted. Living with a global pandemic has become our reality and we are having to get used to many aspects of our...

Vitreomacular traction and full thickness macular hole

1 December 2017 | | EYE - Vitreo-Retinal, EYE - Imaging
Clinical scenario: A 64-year-old lady presented to the clinic with a few weeks history of sudden onset of metamorphopsia, central blur and reduced vision in her right eye. The ocular examination and ocular coherence tomography confirmed right eye focal vitreomacular...

Cataract surgery in uveitis patients

1 February 2016 | | EYE - Cataract, EYE - Refractive
Cataract formation is a common complication of uveitis, causing up to 40% of vision loss in these patients. Cataract results from inflammation +/- corticosteroid therapy and is usually posterior subcapsular, but a small proportion have a rapid increase in nuclear...

The management of possibly progressive pterygium

1 February 2015 | | EYE - Cornea
A 43-year-old Sudanese male patient is referred by his GP with a fleshy lesion encroaching the nasal cornea for the last six months. History Make note of: risk factors, i.e. UV exposure and ocular irritation - history of living in...

Discussing treatment modalities for bilateral wet AMD

1 December 2014 | | EYE - Vitreo-Retinal
A 65-year-old lady with bilateral wet AMD and vision of 6/24 comes with an internet search about current therapies. How do you explain the various treatment modalities available? There are two NICE approved treatments for wet age-related macular degeneration (AMD)....

Ocular electrophysiology

1 April 2014 | | EYE - Oculoplastic, EYE - Orbit
A 34-year-old woman, who is a CEO in a multinational firm, has been losing vision over the last 12 months. She has seen her opticians, who initially tried different glasses but could not improve things. Clinical examination is unremarkable. How...

How to diagnose and treat Acanthamoeba keratitis

1 February 2019 | | EYE - Cornea, EYE - General
Corneal ulceration caused by Acanthamoeba is on the rise, and recent publications indicate an outbreak in the UK over the last few years [1]. Since Acanthamoeba keratitis often presents with atypical features, diagnosis from slit-lamp examination alone can often be...

Cataract surgery supervision

1 June 2019 | | EYE - Cataract, EYE - Refractive, EYE - General
Senior trainees supervising other more junior trainees’ cataract surgery is a skill which needs to be taught and developed with care. It is beneficial for senior trainees as it provides an opportunity to develop supervision techniques prior to consultancy and...