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5367 results found

AMD and visceral fat and pro-inflammatory factors

Several large studies have shown a positive relationship between age-related macular degeneration (ARMD) and high body mass index. The waist-hip ratio is also associated with development of early AMD. Visceral fat has a pro-inflammatory effect, which means it has an...

γδ T cell depletion does not affect fungal keratitis

Fungal keratitis (FK) is a blinding condition prevalent in agricultural areas of countries such as India and China. The fungus enters the cornea and induces an inflammatory response which leads to tissue damage. Neutrophils are the earliest infiltrating immune cells...

The impact of conjunctivochalasis on dry eye symptoms and signs

The study aimed to draw a relationship between conjunctivochalasis and dry eye symptoms via a dry eye questionnaire (DEQ5), as well as signs such as tear osmolarity, tear break up time, corneal staining, Schirmer score, meibomian gland dropout, eye lid...

Allografts in limbal stem cell deficiency

This prospective comparative study compared outcomes of live related limbal allograft (Lr-CLAL) versus cadaveric keratolimbal allograft (KLAL) in limbal stem cell deficiency secondary to ocular burns. Twenty patients were randomly allocated into each group. The Lr-CLAL group had a significant...

Topical atorvastatin for dry eye and blepharitis

Dry eye is a very common problem with 20% of the population affected and is frequently associated with blepharitis (DEB), which has an over prevalence of about 40%. The aim of this study was to evaluate a topical atorvastatin formulation...

Sustained elevation of extracellular ATP in chronic glaucoma

Although adenosine 5′-triphosphate (ATP) release from retinal neurons and astrocytes has been demonstrated in short-term increases in intraocular pressure (IOP); such as in aqueous humor of humans with primary acute angle closure glaucoma, the response in chronic IOP elevation was...

Postural control in glaucoma patients with virtual reality

The authors report on a cross-sectional study evaluating postural control and history of falls in glaucoma patients. History of falls was obtained using the Falls Screening and Referral Algorithm. Postural stability was assessed using a force platform under four conditions:...

A case series of acquired esotropia in cerebellar disease

Acquired esotropia in cerebellar disease is well described but under-recognised. The pathogenesis of cerebellar esotropia is controversial. It is suggested it may be a result of disruption to central vestibular pathways. This article reports a case series of seven adults...

A case of progressive supranuclear palsy-like syndrome following aortic aneurysm repair

This original article illustrates the case of an 18-year-old woman who developed progressive supranuclear palsy-like syndrome following an uneventful aortic aneurysm repair. The patient was unaffected for the first 48 hours after surgery and then developed dysarthria, dysphagia (requiring a...

Conjunctival melanoma involving the lacrimal drainage system

A total of 52 patients were diagnosed with conjunctival melanoma over a period of 17 years, 17 of whom required orbital exenteration. Five of these were found to have melanoma involving the lacrimal drainage apparatus (LDA). One was evident clinically...

Botulinum toxin after orbicularis myectomy

This is a retrospective review of 27 patients with benign essential blepharospasm who had become resistant to treatment with botulinum toxin and had therefore undergone orbicularis myectomy of the upper lids. The study compares the dose and frequency of botulinum...

Screening for ROP using wide-angle digital retinal photography by non-ophthalmologists

This is a systematic review article to evaluate the accuracy of digital retinal photography (DRP) performed by trained personnel (non-ophthalmologists) in diagnosing clinically significant retinopathy of prematurity (ROP). The authors used search engines including Medline, EMBASE, CINAHL and Cochrane databases....