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A phase 3 randomised trial of nicotinamide for skin cancer chemoprevention
To B3, or not to B3? That was the question asked in this controlled trial in which the authors were able to show that oral nicotinamide (vitamin B3) is able to reduce further skin cancer development in high risk patients....
Non-arteritic anterior ischaemic optic neuropathy in the Asian population
This article provides an evaluation of changes in visual function associated with non-arteritic anterior ischaemic optic neuropathy (NAION) among Korean patients. Visual changes were identified as a reduction in visual acuity by three Snellen lines or a deterioration of visual...
Combined anti-VEGF and PDT for wet AMD
The authors report on a retrospective case series of combined anti-VEGF and photodynamic therapy (PDT) in the treatment of wet age-related macular degeneration (AMD) refractory to anti-VEGF monotherapy alone. The criteria for treatment failure of anti-VEGF monotherapy were persistent subretinal...
Endoscopic assisted probing for congenital nasolacrimal duct obstruction
In this retrospective study authors compare the success rate of nasal endoscopic-assisted probing between younger (three years and below) and older (three years and above) children with membranous nasolacrimal duct obstruction and its correlation with the thickness of the membrane...
Comparison of vertical rectus muscle transpositions
The purpose of this study was to evaluate both the amount of correction obtained and the postoperative drift that occurred with two frequently used vertical rectus muscle transposition (VRT) procedures to determine the ideal immediate postoperative alignment. Twenty-seven patients underwent...
Neurofibromatosis type 1 features
The aim in this study was to identify the incidence and de nova mutation rate of Neurofibramatosis type 1 (NF1) and describe the ocular and non-ocular findings in a population-based cohort of patients diagnosed over a 30-year period. The study...
Can retinal layer thickness predict the progression of disability in MS?
This is an observational retrospective cohort study presenting the data of 188 patient diagnoses with multiple sclerosis at two specialist centres. All included patients were adults below the age of 70 years, stable on their disease modifying treatment for at...
BT outcomes for accommodative esotropia
The purpose of this study was to study the effect of Botulinum Toxin (BT) in refractive and non-refractive accommodative esotropia unresponsive to glasses and poor compliance with glasses. This was a retrospective study of 114 patients who had BT for...
Visual prognosis in Irish Leber’s hereditary optic neuropathy
Leber’s hereditary optic neuropathy (LHON) is an inherited optic neuropathy This paper presents a retrospective review of clinical data from patients with LHON presenting to an Irish tertiary referral ophthalmic hospital. Clinical and genetic characteristics were assessed for useful biomarkers...
Treatment of diabetic macular edema in vitrectomised eyes – comparison of intravitreal dexamethasone implant and posterior subtenon triamcinolone injection
This retrospective study was aimed to compare intravitreal dexamethasone implant and posterior subtenon triamcinolone injection (PSTA) in the treatment of diabetic macular edema (DME) in vitrectomised eyes. Sixty-four (48.12%) patients who had received PSTA and 69 (51.88%) patients who had...
Proptosis reduction with teprotumumab versus surgical decompression
This study aims to explore whether fat-to-muscle ratio (FMR) can be used to determine the efficacy of teprotumumab when compared to surgical decompression. Simply put, a high FMR equates to more fat expansion and low FMR equates to more muscle...
