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36 results found

BT outcomes under open versus closed sky technique

3 April 2023 | | Paediatric Ophthalmology / Strabismus
This retrospective study compared open versus closed sky BT injection techniques without electromyography (EMG) control in 135 patients (31 open sky and 104 closed). Patients were aged 1-50 years for open sky and 2-34 years for closed. There was a...

BT for cyclic esotropia

4 February 2021 | | Paediatric Ophthalmology / Strabismus
This paper describes two patients with childhood cyclic esotropia treated with botulinum toxin (BT) and followed for eight and nine years. Onset was at two and four years of age. BT was injected under electromyography (EMG) guidance bilaterally to medial...

Assaying acetylcholine receptor antibodies in the diagnosis of ocular myasthenia

1 December 2022 | | Neuro-Ophthalmology | Ocular myasthenia, anti-acetyl choline receptor antibody, generalised myasthenia
Myasthenia gravis (MG) is an autoimmune disease that leads to impaired neuromuscular transmission. Solely ocular manifestations of MG (OMG) occur in 15-50% of cases, most frequently in the form of fluctuating ptosis and diplopia. Most cases of OMG convert later...

Normal reference values for the RETeval device

1 October 2021 | | Paediatric Ophthalmology / Strabismus
The purpose of this study was to provide normative data of full-field electroretinography (ERG) responses in the paediatric population using the RETeval device in healthy children with normal retinas. This was a prospective study of 38 eyes of 20 patients...

Incidence of ocular myasthenia gravis and risk factors for conversion to generalised disease

1 October 2019 | | Oculoplastics, Orbit
This population based retrospective cohort study evaluates the incidence of ocular myasthenia gravis (OMG) as well as risk factors for transformation to generalised myasthenia gravis (GMG). Sixty-five patients (40 male and 25 female) with newly diagnosed with myasthenia gravis (MG)...
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Globe subluxation subsequent to long-term steroids

7 December 2020 | | Oculoplastics, Orbit
Globe subluxation, when the globe equator projects anterior to the orbital rim, is a serious orbital condition commonly associated with thyroid eye disease, floppy eye syndrome or a shallow orbit. The authors present a first case of a spontaneous globe...

New funding will support development of wearable diagnostics for neuromuscular diseases

1 November 2023 | Hadi Heidari, Glasgow University, Neuromuscular, funding, awards, new technology
A researcher from the University of Glasgow has received an EPSRC Open Fellowship to develop new wearable technology capable of measuring the progress of neuromuscular diseases.

Myasthenia gravis presenting with isolated ptosis: a poorly studied subgroup

1 February 2015 | | Retina / Uvea / Vitreous
Investigation into the cause of one isolated symptom or sign can be challenging if that particular sign may be caused by a variety of pathological processes, affecting different tissues, and presenting to different specialties. Unilateral ptosis is a case in...

A case of Miller Fisher Syndrome and bilateral asymmetric globe retraction

1 February 2022 | | Ophthalmology, Neuro-Ophthalmology
Miller Fisher syndrome (MFS) is a rare, acquired nerve disease that is considered to be a variant of Guillain-Barré syndrome. It was first recognised by James Collier in 1932 as a clinical triad of ataxia, areflexia and ophthalmoplegia. Later, it...

25 years of OCT

1 December 2016 | | Retina / Uvea / Vitreous, Imaging
David Huang first described optical coherence tomography (OCT) in 1991, in his seminal paper on the subject in Science. This method developed the work of others on ophthalmic interferometry, which essentially showed that measuring reflected light could be used to...

Watch your back: Ergonomics and Ophthalmology

2 August 2022 | | Ophthalmology
Aadil Hussain discusses an ophthalmologist’s risk of musculoskeletal injury and highlights the importance of ergonomics education, to ensure a pain-free career. Chronic and disabling musculoskeletal injury has been identified in the field of ophthalmology with increasing prevalence. The ophthalmologist is...

Acetylcholine receptor antibodies in the diagnosis of ocular myasthenia gravis at the Manchester Royal Eye Hospital

3 August 2023 | | Neuro-Ophthalmology
Myasthenia gravis (MG) is the commonest autoimmune condition to affect the neuromuscular junction. In the UK, its prevalence is 15 per 10,000 [1,2] and recent studies have shown that rates are steadily increasing [3,4]. Aims of this audit The aim...
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