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DALK as an early therapeutic option for Acanthamoeba keratitis

Eleven patients with Acanthamoeba keratitis (AK) were treated by early therapeutic deep anterior lamellar keratoplasty (DALK). All surgeries were performed in patients who had no response to standard medical therapy of chlorhexidine gluconate, propamidine isethionate and neomycin sulphate, within 10-15...

γδ T cell depletion does not affect fungal keratitis

Fungal keratitis (FK) is a blinding condition prevalent in agricultural areas of countries such as India and China. The fungus enters the cornea and induces an inflammatory response which leads to tissue damage. Neutrophils are the earliest infiltrating immune cells...

Incidence, microbiological profile and in vitro antimicrobial susceptibility of IK

This is a retrospective single centre study of all patients (with corneal scraping) including their demographic factors, microbiological profiles, and in vitro antibiotic susceptibility of infectious keratitis (IK), studied between 2007 and 2019. The incidence of IK was 34.7/100,000 people...

It’s not always GCA

Giant cell arteritis (GCA) is an immune mediated granulomatous inflammatory disease that affects muscular middle or large sized arteries. It is considered as a continuation of polymyalgia rheumatica (PMR) when the severity of the disease has increased. It is the...

Leadership and management in optometry: why is it important?

The General Medical Council recognises that leadership and management is essential for every doctor, and provides guidance detailing management and leadership responsibilities [1]. Indeed, management and leadership is part of the core training for all medical trainees. However, to date,...

Traumatic optic neuropathy

In neuro-ophthalmology we get asked a lot about management of patients who suffered significant trauma and presented with loss of vision secondary to presumed traumatic optic neuropathy (TON). TON happens usually in the context of significant craniofacial trauma. The incidence...

Fusarium keratitis in a patient with alcohol dependence

Treatment of fungal keratitis secondary to the Fusarium species remains a challenge. Although relatively more common in warmer climates, this corneal infection is rare in the UK. Most cases have been reported in farmers and are often preceded by trauma....

Corneal cross-linking for treatment of corneal ulcers

This was an observational cohort study looking at the usefulness of photo activated chromophore for infectious keratitis-corneal collagen cross-linking (PACK-CXL) in reducing the time to heal in suppurative corneal ulcers. This study, conducted in a tertiary care centre in South...

PUK after corneal crosslinking

This retrospective study aimed to report the incidence, characteristics, clinical presentations, risk factors, and the available treatment modalities of sterile peripheral ulcerative keratitis (PUK) post-corneal collagen crosslinking (CXL). In total 771 eyes of 474 patients operated for keratoconus or ectasia...

Insights in resistant diabetic macular oedema

This article gives a bird’s eye review of the different modalities for the treatment of diabetic macular oedema (DME). The debut of anti-VEGFs has brought a paradigm shift in DME management. This treatment has now become a major breakthrough in...

Troubleshooting in LASIK

Contemporary laser in situ keratomileusis (LASIK) is safe and effective. It remains the dominant intervention in routine refractive surgery for a good reason: predictable results, rapid visual recovery, and relatively simple strategies for revision treatment. Over 95% of patients are...

An uncommon late postoperative complication of combined cataract surgery and intravitreal triamcinolone injection

Case report A 64-year-old female with diabetic maculopathy (DMO) underwent phacoemulsification with intraocular lens (IOL) implantation in her right eye combined with intravitreal triamcinolone (IVTA). Diabetes control was poor with HbA1c (IFCC) of 119mmol/mol and blood sugar level of 27mmol/L....