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31 results found

A clinical review of optic neuropathy associated with amiodarone

The authors present a clinical overview of the occurrence of visual loss secondary to optic neuropathy associated with the use of the antiarrhythmic agent amiodarone. Amiodarone is prescribed for the management of atrial fibrillation and ventricular tachycardia / fibrillation. However,...

Retinal changes in Leber hereditary optic neuropathy

The objective of this study was to describe the changes in the retinal ganglion cell complex (GCC) relative to the retinal nerve fibre layer (RNFL) over time, in patients with Leber’s hereditary optic neuropathy (LHON). For this study, 21 patients...

Leber’s hereditary optic neuropathy outcomes in an Indian population

A large cohort study in an Indian population is presented, with clinical and genetic profile analysis of patients with Leber’s hereditary optic neuropathy (LHON) treated over a five-year period. The study included 157 patients; 143 male, 14 female (10.2:1 ratio)...

Choroidal and macular thickness in nonarteritic anterior ischaemic optic neuropathy

This study evaluates the choroidal and macular thickness in patients with chronic nonarteritic anterior ischaemic optic neuropathy (NA-AION). Two groups of subjects were compared, group one included 20 eyes with chronic NA-AION and group two, 31 healthy control eyes. The...

Non-arteritic anterior ischaemic optic neuropathy in the Asian population

This article provides an evaluation of changes in visual function associated with non-arteritic anterior ischaemic optic neuropathy (NAION) among Korean patients. Visual changes were identified as a reduction in visual acuity by three Snellen lines or a deterioration of visual...

Investigation of blood platelet parameters in anterior ischaemic optic neuropathy

The aim of this clinical retrospective comparative study was to assess the possible relationship between arteritic anterior ischaemic optic neuropathy (AAION) and non-arteritic anterior ischaemic optic neuropathy (NAION) with blood platelet parameters and neutrophil-to-lymphocyte ratio (NLR). The medical records of...

A novel way to distinguish between types of anterior ischaemic optic neuropathy

The authors evaluate the monocyte to high-density lipoprotein (HDL) ratio (MHR) in patients with arteritic and non arteritic anterior ischaemic optic neuropathy (A-AION / NA-AION). A distinction between the two types of AION is essential to begin appropriate treatment, which...

Unusual case presentation of arteritic anterior ischaemic optic neuropathy

The authors present a single case of an 84-year-old man with arteritic anterior ischaemic optic neuropathy, but with unusual features on temporal artery biopsy. He presented with a three-day history of sudden onset of loss of vision in his right...

Visual prognosis in Irish Leber’s hereditary optic neuropathy

Leber’s hereditary optic neuropathy (LHON) is an inherited optic neuropathy This paper presents a retrospective review of clinical data from patients with LHON presenting to an Irish tertiary referral ophthalmic hospital. Clinical and genetic characteristics were assessed for useful biomarkers...

Experiences of patients and their families and the impact of Leber hereditary optic neuropathy

The authors present a qualitative study which aimed to explore the impact of Leber hereditary optic neuropathy (LHON) from diagnosis to present day on both patients and their families. Individuals with LHON and their families were purposively sampled from four...

Non-arteritic anterior ischaemic optic neuropathy (NA-AION): a review

Ischaemic optic neuropathy (ION) is the commonest adult optic neuropathy encountered today in our ageing population, is a common cause of irreversible visual loss and is usually associated with underlying vascular disease. The condition is classified as follows: (a) Anterior...

Risk factors for non-arteritic ischaemic optic neuropathy in an Asian population

The authors reviewed the medical records of 45 Korean patients with non-arteritic anterior ischaemic optic neuropathy (NAION) and 45 healthy controls, in order to determine risk factors for the condition in an Asian population. Previous studies looking at risk factors...