You searched for "gene therapy"
Mimicked tumour seeding due to asteroid hyalosis
A case report is presented of a patient with treated retinoblastoma (RB) who later developed asteroid hyalosis which mimicked tumour seeding. The case was a 37-year-old male with presenting symptoms of vitreous floaters. A unilateral RB was diagnosed at the...
Combined ranibizumab and ablative therapy for Coat’s disease
The aim of this study was to observe the efficacy of intravitreal ranibizumab (IVR) combined with laser photocoagulation or cryotherapy, for Coats’ disease. Patients younger than 16 years of age who were diagnosed with Coats’ disease were included in this...Neovascular AMD: fresh recommendations underline standards of best practice
The management of neovascular age-related macular degeneration (nAMD) has advanced dramatically over the past seven years, with the introduction of targeted new therapies that successfully maintain or improve vision in a majority of affected individuals. It’s a fast moving field,...Toxoplasmosis and the associated retinochoroiditis: important facts and when to treat
Annie SeeWah Tung provides an overview of toxoplasmosis retinochoroiditis, including guidance on which cases should be treated and the treatment options. Toxoplasmosis retinochoroiditis is an infectious condition that is characterised by retinochoroidal lesions commonly in the posterior pole and is...Management of proliferative diabetic retinopathy
Diabetic retinopathy is a major cause of blindness in the working-age population. Due to the worsening global epidemic of diabetes, the incidence of morbidity caused by the disease is set to increase [1]. The prevalence of diabetes in the UK...
Sebaceous gland carcinoma
This is a review of 241 patients diagnosed with periocular sebaceous gland carcinoma which investigates whether age at presentation influences either the clinical presentation or the outcomes of treatment. Twelve percent of patients were classified as young (<40 years old),...
Hidden spread of sebaceous cell carcinoma
This was a review of 29 patients who had undergone orbital exenteration for sebaceous cell carcinoma. Prompted by the increasing use of topical treatments for intraepithelial disease, the authors were keen to discover the frequency of spread of tumour cells...
Ocular adnexal mantle cell lymphoma
In this study the authors compare primary ocular adnexal (OA) mantle cell lymphoma (MCL) with initially systemic MCL occurring over a 30-year period. MCL is a rare form of lymphoma accounting for 5-11% of OA lymphomas and therefore knowledge of...
Yolk sac tumours of the orbit and sinonasal tract
This paper outlines two case reports of patients with yolk sac tumours (YSTs) and carries out a review of the literature on this rare malignancy. YSTs are a type of germ cell tumour and primarily occur in the gonads. Ten...
IOP measures after intraocular chemotherapy
This study aimed to describe the relationship between intravitreal chemotherapy and IOP in children with retinoblastoma and identify risk factors for pronounced elevations. This was a retrospective study of ten cases (ten eyes) with 17 encounters overall. Mean age was...
Using bupivacaine to the medical rectus in addition to lateral rectus recession for convergence insufficiency type intermittent exotropia
This is a retrospective study of 60 paediatric optic pathway glioma (OPG) patients (NF1 or sporadic) presenting to Great Ormond Street between 2003-2017. Median follow-up was 82 months. Analysis was divided into best and worst eye vision representing level quality...
