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Intravitreal dexamethasone implant for diabetic macular oedema

The authors report on the three-year outcomes of the Ozurdex Dexamethasone (DEX) intravitreal implant multi-centre trial for the treatment of diabetic macular oedema (DME). Patients with DME (best-corrected vision of 20/50 to 20/200 and central retinal thickness of ≥300µm) were...

Don’t ignore the black lesion! It might be mucormycosis

Keeping mucormycosis infection in the foreground of your differential diagnosis, especially in those more vulnerable patients, will help save their lives if recognised and managed appropriately. Mucormycosis is a fulminant infection caused by the fungi of the family Mucoraceae. It...

Does bariatric surgery prevent progression of diabetic retinopathy?

The authors report a retrospective observational study of T2DM patients who underwent bariatric surgery between 2009 and 2015. Preoperative and postoperative weight, HbA1c, and annual diabetic retinopathy (DR) screening results were obtained from medical records. Patients with preoperative retinal screening...

Part 1: The Arclight Project – Frugal tech for sight

The Arclight Project is a mix of frugal design, manufacturing, distribution, teaching, research, and advocacy, all wrapped up in a social enterprise based at the University of St Andrews. The project is driven by the high burden of needless blindness...

Risks factors for graft preparation failure in DMEK

Diabetes mellitus (DM) makes it more difficult to prepare descemet membrane epithelial keratoplasty (DMEK) grafts due to the ‘stickiness’ of Descemet’s membrane. This retrospective study examined a classification system, where donors were scored points according to their DM related risk...

Innovation update: key advances in eyecare transformation in the last year

Vishal Shah and his co-authors reflect on examples of innovation in eyecare delivery published in the last year and the implications for the future of eyecare services. The “new normal” is an overused phrase to describe extraordinary measures that have...

RaScaL Study

The RaScaL study was a six month, single-centre, controlled, prospective phase I/II study in which subjects with diabetic macular oedema (DME) and associated peripheral nonperfusion on ultrawide-field fluorescein angiography (UWFA) were randomised to: (1) study arm: ranibizumab (0.5 mg) injection...

Sustainability in eyecare: Are virtual clinics the way forward in the diagnosis and monitoring of retinal disease?

Virtual clinics can be used successfully in screening and management of ocular conditions such as diabetic retinopathy, retinopathy of prematurity and age-related macular degeneration. Virtual clinics should be a considered as a more clinically appropriate modality of consultation, diagnosis and...

Somatostatin protects retinal pericytes

Diabetic retinopathy (DR) is a complication of diabetes, caused by high blood sugar levels damaging the retinal microvasculature. Mechanisms, such as oxidative stress and deposition of advanced glycation end products, leads to glial cell activation and neuronal apoptosis. Pericytes, contractile...

A scoping review of artificial intelligence tools for diabetic retinopathy in low- and middle-income countries

The authors conducted a scoping review to summarise the literature relating to artificial intelligence (AI) tools for diabetic retinopathy (DR) in low- and middle-income countries (LMICs). Eighty-one studies were included, following a comprehensive literature search. The majority of studies were...

Twenty-five years in retina

In the next of our articles celebrating 25 years of Eye News, the authors look at how the retina specialty has changed over this time and ask what the future might hold. Retinal disease management has benefited from great advances...

Macular slippage following macular hole surgery

The treatment of macular holes now involves peeling the internal limiting membrane (ILM) as well as vitrectomy and gas tamponade. It has been noted in previous studies that following an ILM peel the morphology of the macula is different. Tadayoni...