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Microvasculature changes of mCNV after ranibizumab treatment using OCTA

In this study the authors aim to evaluate the vascular changes of myopic choroidal neovascularisation (mCNV) after ranibizumab treatment using optical coherence tomography-angiography (OCTA). The 3×3 OCTA en face images were analysed for the absence / presence of mCNV, CNV...

Corneal Topography in Clinical Practice (Pentacam System)

This book is based upon one device, the Pentacam, developed by OCULUS, and is primarily aimed at those who wish to familiarise themselves with the Pentacam system and need a text to complement the instrument operations manual. It is laid...

Twenty-five years in retina

In the next of our articles celebrating 25 years of Eye News, the authors look at how the retina specialty has changed over this time and ask what the future might hold. Retinal disease management has benefited from great advances...

RaScaL Study

The RaScaL study was a six month, single-centre, controlled, prospective phase I/II study in which subjects with diabetic macular oedema (DME) and associated peripheral nonperfusion on ultrawide-field fluorescein angiography (UWFA) were randomised to: (1) study arm: ranibizumab (0.5 mg) injection...

The natural history of treatment naïve choroidal neovascularisation (CNV) in geographic atrophy

The aim of this retrospective study is to assess the characteristics and natural history of quiescent CNV in geographic atrophy (GA) utilising multi-modal imaging. Case notes were reviewed of patients diagnosed with geographic atrophy between January 2010 and December 2016...

RPE tears after intravitreal Lucentis

The current hypothesis regarding retinal pigment epithelium (RPE) tears is the contraction and fibrosis in choroidal neovascularisation (CNV) tissue after anti-VEGF therapy can induce rips in the overlying RPE. This South Korean study aimed to identify the association between RPE...

OCT-A imaging in Grave’s orbitopathy and orbital decompression

In this case series of 12 patients and 24 orbits, the authors describe the changes in the optic nerve and peripapillary blood vessel density in patients with moderate to severe Grave’s Orbitopathy (GO) undergoing orbital decompression. The patients undergoing orbital...

Migraine attack: does retinal and peripapillary blood flow change?

This prospective clinical study compared retinal and peripapillary blood flow parameters in migraine patients during an attack with healthy controls using optical coherence tomography angiography (OCTA). OCTAs were performed on 52 eyes from 26 migraine sufferers and 48 eyes from...

Macular measurements for amblyopic eyes

This study aimed to evaluate the macular parameters including foveal avascular zone (FAV) size and vessel density in amblyopia vs fellow eyes. The study included 23 unilateral amblyopia children (9.86 ±3.12 years; 52.2% female) and non-amblyopia control eyes (8.67 ±2.06...

Assessing failure of laser coagulation treatment for type 1 retinopathy of prematurity

The authors present the findings of a retrospective study to examine the cause of treatment failures in type 1 retinopathy of prematurity (ROP). They reviewed the medical charts of all infants with persistent disease post laser treatment at Uppsala University...

25 years of OCT

David Huang first described optical coherence tomography (OCT) in 1991, in his seminal paper on the subject in Science. This method developed the work of others on ophthalmic interferometry, which essentially showed that measuring reflected light could be used to...

Technology in ophthalmology – a promising future and what we need to know about the regulations

Undoubtedly, ophthalmology is one of the greatest sources of inspiration for technological progress in medicine. Thus far, we have seen remarkable advancements in the technology used by ophthalmologists across all subspecialties. From simplifying common procedures, to treating previously incurable conditions,...