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186 results found
British Journal of Ophthalmology cover image.

Incidence, microbiological profile and in vitro antimicrobial susceptibility of IK

1 December 2021 | | Cornea / External Eye Disease | cornea, epidemiology, infection, microbiology, Ocular surface
This is a retrospective single centre study of all patients (with corneal scraping) including their demographic factors, microbiological profiles, and in vitro antibiotic susceptibility of infectious keratitis (IK), studied between 2007 and 2019. The incidence of IK was 34.7/100,000 people...

Cataract in patients with pseudoexfoliation syndrome

1 August 2018 | | Cataract and Refractive | Apoptosis, TUNEL, cataract, lens epithelial cell, pseudoexfoliation syndrome
The authors present a prospective comparative study in 43 patients with (group 1) or without (group 2) pseudoexfoliation (PXF) undergoing cataract surgery. Anterior capsule samples were obtained in all patients and analysed for signs of apoptosis by using special staining...

Histopathological changes in rabbit retinitis pigmentosa

1 April 2017 | | Neuro-Ophthalmology | Optic disc, optic nerve, rabbit, retinal ganglion cell, retinitis pigmentosa
The authors report the histopathological changes of retinal ganglion cells (RGCs), optic disc and optic nerve in rabbit with advanced retinitis pigmentosa (RP). RP was recreated in rabbits by using bacterial artificial chromosome transgenesis, with the purpose of increasing understanding...

Endothelial cell loss using different graft injectors in DMEK

1 August 2016 | | Cornea / External Eye Disease
This study aimed to investigate endothelial cell loss between two injector systems in descemet membrane endothelial keratoplasty (DMEK) grafts; a glass injector – modified Jones tube and a plastic injector – closed system IOL injector, the Viscoject 2.2 system. DMEK...

Acanthamoeba ability to adhere to different contact lenses

1 June 2016 | | Cornea / External Eye Disease
This study tested ability of Acanthamoeba lugdunensis trophozoites to adhere to silicon hydrogel contact lenses (SHCL) and how this is influenced by different multipurpose contact lens solutions (MPS). Three generations of SHCL were tested: first generation – Air Optix, second...

Fungi in chronic anterior blepharitis

1 June 2016 | | Oculoplastics, Orbit
In this prospective, non-randomised cross-sectional study the authors demonstrate the presence of fungi in patients with chronic anterior blepharitis of at least two years duration. Eyelash samples were obtained by epilation with sterile forceps and evaluated with PAS staining, fungal...

Climatic droplet keratopathy

1 December 2015 | | Cornea / External Eye Disease | UV-B, ascorbate, environment, human, keratopathy
Climatic droplet keratopathy (CDK) is an acquired and potentially handicapping corneal degenerative disease that is highly prevalent in certain rural communities around the world. It predominantly affects males in their 40’s and is known by many other names such as...

SS-MIOCT for suture depth

1 February 2018 | | Paediatric Ophthalmology / Strabismus
The authors describe a case in which swept-source microscope-integrated OCT (SS-MIOCT) was used to directly visualise and evaluate key suturing-related steps of strabismus surgery in real time. Using SS-MIOCT, the surgeons could visualise the precise depth of the needle through...

Macular holes: A brief review

1 August 2017 | | Retina / Uvea / Vitreous
The classification of macular holes has been modernised by OCT findings. This is a brief review and encompasses the historical literature on macular holes. A macular hole is an anatomical discontinuation of the neurosensory retina at the centre of the...

Sustainability in eyecare: Are virtual clinics the way forward in the diagnosis and monitoring of retinal disease?

2 August 2021 | | Ophthalmology, Optometry, Retina / Uvea / Vitreous
Virtual clinics can be used successfully in screening and management of ocular conditions such as diabetic retinopathy, retinopathy of prematurity and age-related macular degeneration. Virtual clinics should be a considered as a more clinically appropriate modality of consultation, diagnosis and...

Real-world experience and outcomes of SLT laser used as a first-line treatment in ocular hypertension patients in a United Kingdom National Health Service setting

3 October 2022 |
The management of raised intraocular pressure (IOP) in the context of ocular hypertension (OHT) and primary open angle glaucoma (POAG) remains a major contributor to the workload of ophthalmology units across the UK. Treatment of these conditions has historically centred...

Optical coherence tomography – reinventing the eye examination

1 October 2016 | | Retina / Uvea / Vitreous, Imaging
It has been 25 years since Huang et al. presented the first optical coherence tomography (OCT) images in Science [1]. With vast improvements in OCT technology over the years, it is now possible to acquire high-resolution cross-sectional images of the...