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Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants
“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...Irido-corneal endothelial syndrome: an overview
Irido-corneal endothelial (ICE) syndrome is a rare group of eye related disorders that constitute three different clinical entities: Chandler syndrome (CS), essential / progressive iris atrophy and iris naevus / Cogan-Reese syndrome. ICE syndrome is sporadic in its presentation as...
Adjuvant oral voriconazole or oral ketoconazole for fungal keratitis
This randomised double-blinded trial examined clinical outcomes of 50 patients with severe fungal keratitis treated with either adjuvant oral voriconazole or oral ketoconazole. Inclusion criteria were culture or smear proven fungal ulcers >5mm in maximum diameter, involving >4mm of the...
Corneal biomechanics and refractive outcomes after cataract surgery
The authors aimed to study a range of corneal properties and correlate them with refractive outcomes after phacoemulsification. Outcomes were reviewed in a fairly small group of 40 patients (including only right eyes) operated by two surgeons using clear corneal...175 years of Ernst Fuchs: The man behind the eponyms
14 June 2026 marked 175 years since the birth of Professor Ernst Fuchs: a teacher, writer, pathologist and one of the great founders of modern ophthalmology, whose name echoes through clinics, exams and theatres worldwide to this day. Most doctors...PACK-crosslinking for infectious keratitis
Corneal cross-linking with riboflavin and UV-A light (CXL) is a technology that has been initially developed to treat corneal ectatic disorders [1]. Its effect in stabilising diseases such as keratoconus was reported in numerous trials with excellent long-term outcomes and...Chemical injury
You are the on-call ophthalmologist. You receive a call from A&E regarding a 45-year-old man who sustained a chemical injury. He was mixing some cement, when a small amount entered his left eye. He was not wearing any protective goggles....
Factors influencing the outcome of GT and TBT in PCG
This is a retrospective study between 2013 to 2016 of 452 eyes of patients </=12 years with primary congenital glaucoma (PCG), who underwent either goniotomy (GT) (median age: six months, 120 eyes) or trabeculotomy (TBT) (median age: 5.2 months, 332...
