Journal Reviews archive for 2015
Adolescent optic disc haemorrhages
The authors conducted this study to describe the clinical characteristics of multi-layered optic disc haemorrhages in adolescents. This was a retrospective review of 16 eyes (11 right and five left) of 16 patients with a mean age of 15 ±2.6...
Masked bilateral SO palsy
This study examined the occurrence of masked bilateral superior oblique (SO) palsy with contralateral inferior oblique (IO) over action requiring further surgical intervention in children undergoing unilateral IO weakening surgery for presumed unilateral SO palsy. This retrospective study included 50...
Slanted MR surgery for convergence excess ET
The authors aimed to evaluate the surgical outcomes of bilateral slanted recessions of the medial rectus (MR) muscles in patients with convergence excess esotropia (ET). This retrospective study included 16 patients with a mean age at surgery of 5.6 ±3.05...
Ranibizumab for the treatment of age-related macular degeneration
This multicentre randomised prospective open label study compared 0.5 versus 2mg of ranibizumab in patients with submacular retinal pigment epithelial (RPE) detachment due to age-related macular degeneration. Four treatment regimens were used for the two strengths either monthly for 12...
Aflibercept, bevacizumab or ranibizumab for diabetic macular oedema
Macular oedema (MO) is a leading cause of visual impairment in patients with diabetic retinopathy. Whilst laser photocoagulation therapy has been the proven treatment for decades, studies over the last five years have also established a role for anti-VEGF agents...
Three years of experience with quantiferon-TB Gold Testing in patients with uveitis
Quantiferon-TB Gold is a new alternative to the tuberculin skin test that utilises synthetic peptides representing M. tuberculosis antigens ESAT-6, CFP-10, TB7.7 and upon incubation with whole blood IFN-γ is released from pre-sensitised T cells and can be measured by...
Aqueous humour cytokine levels in PCV and nAMD
This study looks into the possible roles of various cytokines or growth factors in the pathogenesis of exudative age-related macular degeneration (AMD) by comparing aqueous levels of 14 cytokines between eyes with polypoidal choroidal vasculopathy (PCV) and those with neovascular...
Intravitreal ranibizumab for the treatment of myopic CNV
The authors conducted a prospective study. Sixty-four patients (65 eyes) attended the 12-month follow-up examination. The mean patient age was 47.8 years. Fifty-five patients (86.0%) were females. All patients had pathologic myopia (a spherical equivalent of more than − 6.0...
Hyper reflective foci (HRF) on OCT in diabetic retinopathy
This study investigated the presence of hyper reflective foci (HRF) in asymptomatic patients affected by type 1 or type 2 diabetes, separately, without clinically significant diabetic macular oedema and visual impairment. In total 71 eyes with non-proliferative diabetic retinopathy were...
VEGF and axial length (RVU)
The authors of this paper set out to examine whether the concentrations of VEGF in the vitreous were associated with refractive error and axial length in eyes without retinal disease, except of macular holes or epiretinal membranes. A vitreous sample...
Intravitreal injection related endophthalmitis
This article reviews the incidence, clinical findings, risk factors, management and visual outcomes in intravitreal injection related endophthalmitis. Incidence of this complication is reported to be in the range of 0.038% to 0.065% (1 in 2000-3000 injections). Patients present typically...
Nasolacrimal duct screening to minimise post cataract endophthalmitis
This case control study compared the nasolacrimal duct (NLD) patency in a random sample of phacoemulsification cataract surgery patients (control group) versus a consecutive series of patients who developed endophthalmitis post cataract surgery (case group). NLD syringing was performed in...
