Journal Reviews
Detecting apoptosis in retinal cells
This is a review paper in which the authors summarise the transitioning of techniques detecting apoptosis from bench to bedside, along with the future possibilities they encase. Detection of Apoptosis in Retinal Cells (DARC) technology can be used as a...
Cell injection therapy for endothelial failure
This is a prospective observational study involving 11 eyes of 11 patients with pseudophakic endothelial failure who underwent human corneal endothelial cell culture (hCEC) injection therapy for endothelial failure. This study aimed to evaluate the long-term five-year postoperative data for...
Refraction under GA in children using cycloplegic refraction as a reference
The authors aimed to compare the measurements of cycloplegic refraction and refraction (R1-1) under general anaesthesia (GA) with automated refraction (ARF) in paediatric patients and to determine the impact of GA on accommodation. The study included 222 eyes of 222...
The effects of anti-VEGF therapy for NvAMD on retinal vasculature
This retrospective consecutive case series examined 54 eyes of 54 treatment-naïve neovascular age-related macular degeneration (N-AMD) patients. Thirty-three eyes received intravitreal aflibercept injections, and 21 eyes received intravitreal ranibizumab injections with unaffected fellow eyes (54 eyes) as controls. All image...
OCTA in geographic atrophy
In this article the authors aim to give an overview of the current literature concerning the application of OCT-A in geographic atrophy (GA). GA is a disease characterised by loss of outer retinal layers including photoreceptors, degeneration of the retinal...
Microdroplet and splatter contamination during phacoemulsification in COVID-19 era
Half a millilitre of fluorescein was incorporated into 400ml of balanced salt solution to identify microdroplet and splatter from phacoemulsification to simulate possible COVID-19 contamination. Five porcine eyes were mounted to an ophthalmic mannequin head and two surgeons (height 189cm,...
Wet AMD outcomes post cataract surgery
The authors present the findings of a retrospective study looking at the progression of wet age-related macular degeneration (AMD) in patients who underwent cataract surgery. They recruited a series of 111 patients of which 38 were men and 73 were...
Characteristics of Charles Bonnet syndrome in patients with neovascular AMD
This retrospective cross-sectional study aimed to characterise various aspects of Charles Bonnet syndrome hallucinations among patients with neovascular age-related macular degeneration (AMD). Five hundred and ten consecutive patients were asked a screening question to determine if they had ever suffered...
Changes in drusen and retinal layer volumes prior to CNV development
This retrospective longitudinal study looked at patients with wet age-related macular degeneration (AMD) in one eye who subsequently developed wet AMD in the fellow eye. The aim was to discover whether drusen characteristics or volumes of retinal layers correlate with...
Effect of blue-light filtering intraocular lenses on age-related macular degeneration
This is a retrospective cohort study evaluating whether blue-light filtering (BLF) intraocular lenses (IOL) offer prophylaxis for neovascular age-related macular degeneration (nAMD). The study included 11,397 eyes of 11,397 patients with a mean age of 75.4 ±8.3 years that underwent...
Restoration of colour perception in patients with retinitis pigmentosa
This is a case series testing the feasibility of using bioelectronic retinal prostheses to partially restore colour perception in seven patients with advanced retinitis pigmentosa. Bioelectronic retinal prostheses are able to bypass degenerated photoreceptors to directly stimulate the inner retinal...
Orbital manifestations of granulomatosis with polyangitis
This a retrospective, observational study where authors looked at the ophthalmological examination, biopsy, antibodies and CT scan results of all patients diagnosed with granulomatosis with polyangitis (GPA) from January 2007-January 2019. Out of 101 patients with diagnosis of GPA, 15...
