Journal Reviews

Akimba mice, a model of human diabetic retinopathy

1 October 2014 | | Retina / Uvea / Vitreous | Akimba, BRB, PLVAP, blood-retinal barrier, diabetic macular edema, diabetic retinopathy, mouse models, retina

Diabetic retinopathy (DR) is a major complication of diabetes and a growing problem as the systemic disease becomes more prevalent. DR develops insidiously from an asymptomatic form through to vascular damage that leads to oedema and breakdown of the blood-retinal...